Sestamibi (99mTc) scan as a single localization modality in primary hyperparathyroidism and factors impacting its accuracy

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Differences in accuracy of 99mTc-sestamibi scanning between severe and mild forms of primary hyperparathyroidism.

UNLABELLED Preoperative localization of the parathyroids using (99m)Tc-sestamibi scanning has not yet been established as a routine diagnostic procedure for primary hyperparathyroidism. Several studies have demonstrated a variable degree of accuracy (70%-98%) in asymptomatic patients. METHODS We evaluated the accuracy of this technique in 64 patients who underwent scanning between January 200...

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99mTc-sestamibi and minimally invasive radioguided surgery for primary hyperparathyroidism.

The management of primary hyperparathyroidism is not without controversy. There is controversy as to which imaging technique (if any) should be used to localize a parathyroid adenoma (1,2). There is controversy as to when surgery should be recommended in an asymptomatic patient; although some would argue that all patients are symptomatic but simply do not realize it! There is also controversy a...

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Comparison of 99mTc-sestamibi and 11C-methionine PET/CT in the localization of parathyroid adenomas in primary hyperparathyroidism.

AIM To evaluate the usefulness of (11)C-methionine PET/CT (MET) in the localization of the parathyroid adenomas and to compare the results with those obtained with the conventional technique in double-phase (99m)Tc-sestamibi scintigraphy (MIBI). We evaluated the optimal timing to acquire MET images. MATERIAL AND METHODS A prospective study that included 14 patients (mean age: 65.5 ± 9.7 years...

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Parathyroid scintigraphy in patients with primary hyperparathyroidism: 99mTc sestamibi SPECT and SPECT/CT.

The clinical diagnosis of primary hyperparathyroidism is based largely on serum laboratory test results, as patients often are asymptomatic. Surgery, often with bilateral exploration of the neck, has been considered the definitive treatment for symptomatic disease. However, given that approximately 90% of cases are due to a single parathyroid adenoma, a better treatment may be the selective sur...

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Minimally invasive radionuclide-guided parathyroidectomy using 99mTc-sestamibi in patients with primary hyperparathyroidism: a single-institution experience.

OBJECTIVE To evaluate the efficacy and usefulness of (99m)Tc-sestamibi scintigraphy and gamma probe localization of parathyroid glands in patients with primary hyperparathyroidism and establish radio-guided minimally invasive parathyroidectomy at Hussain Makki Al Jumma Center for Specialized Surgery, Kuwait. SUBJECTS AND METHODS Twelve patients with primary hyperparathyroidism (mean age: 48 +...

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ژورنال

عنوان ژورنال: Indian Journal of Nuclear Medicine

سال: 2010

ISSN: 0972-3919

DOI: 10.4103/0972-3919.63591